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mebendazole  

Dosage form
Rationale for inclusion in the
WHO Model List of Essential Medicines
Type of EML
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chewable tablet, 100 mg, 500 mg
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For threadworm, roundworm, whipworm and hookworm.

No systematic reviews but randomized controlled trials exist.
(Cochrane Library: 2002 Issue 1)

Note: the Expert Committee, April 2003, considered the following medicines to have similar clinical effect; albendazole, flubendazole.

Please see references 1 and 2 for use during pregnancy/lactation and in young children.

ATC Code: P02CA01
Core List

 

Indications (Diseases)


Cestodes (tapeworm) - echinococcosis
IMCI (Integrated management of childhood illness)
Iron deficiency anaemia
Nematodes - ascariasis
Nematodes - capillariasis
Nematodes - enterobiasis
Nematodes - hookworm
Nematodes - trichinellosis
Nematodes - trichuriasis
Postpartum haemorrhage

References

1. .html
Report of the WHO Informal Consultation on the use of praziquantel during pregnancy/lactation and albendazole/mebendazole in children under 24 months, Geneva, 8-9 April, 2002, WHO/CDS/CPE/PVC/2002.4
   http://www.who.int/wormcontrol/documents/en/pvc_20024full.pdf

2. .html
Benzimidazoles: use in children, Essential Medicines, WHO Drug Information, Vol 17, No. 1, 2003
   http://www.who.int/druginformation/vol17num1_2003/vol17-1.pdf


Links

1. Model Formulary search
2. Model List search
3. International Drug Price Indicator Guide Search (Management Sciences for Health)
4. ATC/DDD
5. International Nonproprietary Names - INN
6. WHO Collaborating Centre for International Drug Monitoring  WHO Adverse drug reaction search