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Microsporidiosis infection (HIV/AIDS)

Introduction, etiology

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The two most important species are Enterocytozoon bieneusi and Encephalitozoon intestinalis. The most common manifestation of intestinal microsporidiosis in HIV-positive patients is profuse, watery, non-bloody diarrhoea, sometimes accompanied by abdominal pain and cramping, nausea, vomiting and weight loss.

Recommended treatments

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albendazole
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chewable tablet, 400 mg

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Adults:
400 mg twice a day for 4 weeks

References
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WHO Model Prescribing Information. Drugs used in HIV-related infections, WHO/DMP/DSI/99.2.
   http://www.who.int/medicines/library/qsm/who-dmp-dsi-99-2/who-dmp-dsi-99-2.htm
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Report of the WHO Informal Consultation on the use of praziquantel during pregnancy/lactation and albendazole/mebendazole in children under 24 months, Geneva, 8-9 April, 2002, WHO/CDS/CPE/PVC/2002.4
   http://www.who.int/wormcontrol/documents/en/pvc_20024full.pdf
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Benzimidazoles: use in children, Essential Medicines, WHO Drug Information, Vol 17, No. 1, 2003
   http://www.who.int/druginformation/vol17num1_2003/vol17-1.pdf
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International Travel and Health, World Health Organization, 2003, ISBN 92 4 158028 3
   http://www.who.int/ith/

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