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Infection is transmitted by eggs or larvae, which begin their cycle of development within the human host when, depending on the species, they either actively penetrate intact skin or are ingested or, very rarely, inhaled. The larvae of the most widely prevalent species remain dormant but potentially infective for long periods in contaminated soil; the larvae or cysts of other species are ingested when the flesh of reservoir hosts is eaten either raw or undercooked.

Trichuriasis, or whipworm infection, which is caused by the nematode worm Trichuris trichiura, is estimated to affect some 1050 million people and of these, an estimated 10 000 die annually (2002). Children aged 5 to 14 years are particularly vulnerable. Most cases occur in the moist, warm, tropical regions of Asia, Africa, Central and South America, and the Caribbean islands.

chewable tablet, 100 mg, 500 mg

Adults and children over 2 years:
For mild to moderate infections: A single dose of 500 mg
Heavier infections: 500 mg for 3 consecutive days

chewable tablet, 400 mg

Adults and children over 2 years:
For mild to moderate infections: A single dose of 400 mg
Heavier infections: 400 mg for 3 consecutive days

WHO Model Prescribing Information. Drugs used in parasitic diseases second edition, 1995. 146 pages [E, F, S] ISBN 92 4 140104 4 Sw.fr. 35.-/US $31.50. In developing countries Sw.fr.24.50.

Intestinal nematodes, WHO link page

Parasites and Health, Trichuriasis, Centers for Disease Control and Prevention, USA

Report of the WHO Informal Consultation on the use of praziquantel during pregnancy/lactation and albendazole/mebendazole in children under 24 months, Geneva, 8-9 April, 2002, WHO/CDS/CPE/PVC/2002.4

Benzimidazoles: use in children, Essential Medicines, WHO Drug Information, Vol 17, No. 1, 2003


mebendazole .html chewable tablet, 100 mg, 500 mg	.html Adults and children over 2 years: For mild to moderate infections: A single dose of 500 mg Heavier infections: 500 mg for 3 consecutive days
or albendazole .html chewable tablet, 400 mg	.html Adults and children over 2 years: For mild to moderate infections: A single dose of 400 mg Heavier infections: 400 mg for 3 consecutive days

1.	.html WHO Model Prescribing Information. Drugs used in parasitic diseases second edition, 1995. 146 pages [E, F, S] ISBN 92 4 140104 4 Sw.fr. 35.-/US $31.50. In developing countries Sw.fr.24.50.
	Sales Information: http://www.who.int/bookorders/index.htm
2.	.html Intestinal nematodes, WHO link page
	http://www.who.int/health-topics/intestinal.htm
3.	.html Parasites and Health, Trichuriasis, Centers for Disease Control and Prevention, USA
	http://www.dpd.cdc.gov/dpdx/HTML/Trichuriasis.htm
4.	.html Report of the WHO Informal Consultation on the use of praziquantel during pregnancy/lactation and albendazole/mebendazole in children under 24 months, Geneva, 8-9 April, 2002, WHO/CDS/CPE/PVC/2002.4
	http://www.who.int/wormcontrol/documents/en/pvc_20024full.pdf
5.	.html Benzimidazoles: use in children, Essential Medicines, WHO Drug Information, Vol 17, No. 1, 2003
	http://www.who.int/druginformation/vol17num1_2003/vol17-1.pdf

Nematodes - trichuriasis

Introduction, etiology

Recommended treatments

Model Formulary search